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The Institute for EthnoMedicine BMAA molecule, produced by cyanobacteria and believed to be a neurotoxin
 
 

As a not-for-profit organization headquartered in Jackson Hole, Wyoming, our mission is to discover new cures from plants. With a state-of-the art laboratory in Jackson, as well as an additional laboratory in Southern California, we have assembled a team of researchers who are working tirelessly to find and fight causes of disease and to search for new cures from plants.

Current projects of the Institute include:

  • Ethnobotanical studies of the Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) disease among the Chamorro people of Guam and villagers of the Kii Peninsula of Japan; » More
     
  • Development of village-based pharmaceutical industries in Samoa, including the antiviral HIV-1 targeted drug Prostratin; » More
     
  • Studies of consumption of cyanobacteria and cyanobacterial products by indigenous peoples in China, Africa, and South America. » More

Our studies of remote Pacific island villages with high levels of ALS led to reconsideration of BMAA—a toxic amino acid—as a possible trigger for certain neurodegenerative illnesses in genetically vulnerable individuals. We and our collaborators have found that BMAA is produced by cyanobacteria which occur throughout the world.

We have developed techniques to detect BMAA at extremely low concentrations in water supplies and human tissues. If BMAA does indeed serve as an environmental trigger for sporadic ALS, our research will help identify those individuals who are vulnerable to the cyanobacterial toxin. We also are exploring new approaches to ALS therapy based on BMAA research.

Flying Fox in Cycad Tree, the center of the research around BMAA and ALS